This study covers one of the many applications of BIOiSIM. Our aim was to establish what the pharmacokinetic (PK) profile would look like in the different subjects studied.
This white paper showcases how modeling and simulation can be used to successfully predict the disposition of small molecules across different subjects.
This study covers the development and validation of a transdermal model using the BIOiSIM framework, which was further used to describe the relationship between compound exposure and therapeutic effect.
This study covers one of the many applications of BIOiSIM, simulation of drug disposition after IV administration. Our aim was to train the model on in vivo rat compound data and enable it to perform pharmacokinetic (PK) predictions for IV-administered…